Publications
2021
Shanti Pal Gangwar, Marriah N. Green, Erwan Michard, Alexander A. Simon, José A. Feijó, Alexander I. Sobolevsky
«Structure of the Arabidopsis Glutamate Receptor-like Channel GLR3.2 Ligand-Binding Domain »,
Structure ,
2021, Volume 29, Issue 2, 161-169.e4
2020
Rajesh Bhardwaj, Sonja Lindinger, Arthur Neuberger, Kirill D. Nadezhdin, Appu K. Singh, Micael R. Cunha, Isabella Derler, Gergely Gyimesi, Jean-Louis Reymond, Matthias A. Hediger, Christoph Romanin, Alexander I. Sobolevsky
«Inactivation-mimicking block of the epithelial calcium channel TRPV6 »,
Science Advances ,
2020, Vol. 6, no. 48
Maria V. Yelshanskaya, Appu K. Singh, Chamali Narangoda, Robin S.B. Williams, Maria G. Kurnikova, Alexander I. Sobolevsky
«Structural basis of AMPA receptor inhibition by 4-BCCA »,
British Journal of Pharmacology ,
2020, p. 1-17
Riley E Perszyk, Scott J Myers, Hongjie Yuan, Alasdair J Gibb, Hiro Furukawa, Alexander I Sobolevsky, Stephen F Traynelis
«Hodgkin-Huxley-Katz Prize Lecture: Genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif »,
Journal of Physiology ,
2020, 598(15): 3071–3083
Yelshanskaya MV, Nadezhdin KD, Kurnikova MG, Sobolevsky AI.
«Structure and function of the calcium-selective TRP channel TRPV6 »,
J. Physiology ,
2020, Feb 19., p.1-25
2019
Shanti Pal Gangwar, Marriah Green and Alexander I. Sobolevsky
«Structure of the Glutamate-Like Receptor GLR3.2 ligand-binding domain »,
BioRxiv ,
2019, (Dec 24): 1-22
Appu K. Singh, Luke L. McGoldrick, Lusine Demirkhanyan, Merfilius Leslie, Eleonora Zakharian and Alexander I. Sobolevsky
«Structural basis of temperature sensation by the TRP channel TRPV3 »,
Nature Structural & Molecular Biology ,
2019, 26: 994–998
Edward C. Twomey, Maria V. Yelshanskaya, Alexander I. Sobolevsky
«Structural and functional insights into transmembrane AMPA receptor regulatory protein complexes »,
Journal of General Physiology ,
2019, 1540-7748
Luke L. McGoldrick, Appu K. Singh, Lusine Demirkhanyan, Ting-Yu Lin, Ryan G. Casner, Eleonora Zakharian, Alexander I. Sobolevsky
«Structure of the Thermo-Sensitive TRP Channel TRP1 from the Alga Chlamydomonas Reinhardtii »,
Nature Communications ,
2019, Sept 13; 10(1):4180.
Lucie Macikova, Lenka Vyklicka, Ivan Barvik, Alexander I. Sobolevsky, Viktorie Vlachova
«Cytoplasmic Inter-Subunit Interface Controls Use-Dependence of Thermal Activation of TRPV3 Channel »,
International Journal of Molecular Science ,
2019, 20(16), 3990
Appu K. Singh, Luke L. McGoldrick, Alexander I. Sobolevsky
«Expression, Purification, and Crystallization of the Transient Receptor Potential Channel TRPV6 »,
Methods in Molecular Biology ,
2019, volume 1987: pp 23-37
2018
Alexander I. Sobolevsky
«Influences: Russian training »,
Journal of General Physiology ,
2018, 150: 1596-1598
Appu K. Singh*, Luke L. McGoldrick*, Alexander I. Sobolevsky
«Structure and gating mechanism of the transient receptor potential channel TRPV3 »,
Nature Structural & Molecular Biology ,
2018, 25: 805-813
Edward C. Twomey, Maria V. Yelshanskaya, Alexander A. Vassilevski, Alexander I. Sobolevsky
«Mechanisms of channel block in calcium-permeable AMPA receptors »,
Neuron ,
2018, 99: 956-968
Appu K.Singh*, Luke McGodrick*, Edward C. Twomey, Alexander I. Sobolevsky
«Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6 »,
Science Advances ,
2018, 4 (8): eaau6088
Appu K. Singh*, Kei Saotome*, Luke L. McGoldrick, Alexander I. Sobolevsky
«Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB »,
Nature Communications ,
2018, 9: 2465
Appu K. Singh, Luke L. McGoldrick, Kei Saotome, Alexander I. Sobolevsky
«X-ray crystallography of TRP channels »,
Channels ,
2018, 12: 137-152
Serzhan Sakipov, Alexander I. Sobolevsky, Maria G. Kurnikova
«Ion permeation mechanism in epithelial calcium channel TRVP6 »,
Scientific Reports ,
2018, 8: 5715
Dmitry I. Osmakov, Sergey G. Koshelev, Yaroslav A. Andreev, Maxim A. Dubinnyi, Vadim S. Kublitski, Roman G. Efremov, Alexander I. Sobolevsky, Sergey A. Kozlov
«Proton-independent activation of acid-sensing ion channel 3 by an alkaloid, lindoldhamine, from Laurus nobilis »,
British Journal of Pharmacology ,
2018, 175 (6): 924-937
Luke L. McGoldrick*, Appu K. Singh*, Kei Saotome, Maria V. Yelshanskaya, Edward C. Twomey, Robert A. Grassucci, Alexander I. Sobolevsky
«Opening of the human epithelial calcium channel TRPV6 »,
Nature ,
2018, 553: 233-237
Edward C. Twomey, Alexander I. Sobolevsky
«Structural mechanisms of gating in ionotropic glutamate receptors »,
Biochemistry ,
2018, 57 (3): 267-276
Appu K. Singh, Kei Saotome, Alexander I. Sobolevsky
«Determining the crystal structure of TRPV6 »,
Calcium Entry Channels in Non-Excitable Cells ,
2018, ISBN 978-1-4987-5272-5
2017
Appu K. Singh, Kei Saotome, Alexander I. Sobolevsky
«Swapping of transmembrane domains in the epithelial calcium channel TRPV6 »,
Scientific Reports ,
2017, 7: 10669
Edward C. Twomey, Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, Alexander I. Sobolevsky
«Channel opening and gating mechanism in AMPA-subtype glutamate receptors »,
Nature ,
2017, 549: 60-65
Edward C. Twomey, Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, Alexander I. Sobolevsky
«Structural bases of desensitization in AMPA receptor-auxiliary subunit complexes »,
Neuron ,
2017, 94 (3): 569-580.E5
Maria V. Yelshanskaya, Samaneh Mesbahi-Vasey, Maria G. Kurnikova, Alexander I. Sobolevsky
«Role of the ion channel extracellular collar in AMPA receptor gating »,
Scientific Reports ,
2017, 7: 1050
2016
Maria V. Yelshanskaya, Appu K. Singh, Jared M. Sampson, Chamali Narangoda, Maria Kurnikova, Alexander I. Sobolevsky
«Structural bases of noncompetitive inhibition of AMPA-subtype ionotropic glutamate receptors by antiepileptic drugs »,
Neuron ,
2016, 91 (6): 1305-1315
Edward C. Twomey, Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, Alexander I. Sobolevsky
«Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy »,
Science ,
2016, 353 (6294): 83-86
Kei Saotome, Appu K. Singh, Maria V. Yelshanskaya, Alexander I. Sobolevsky
«Crystal structure of the epithelial calcium channel TRPV6 »,
Nature ,
2016, 534: 506-511
Maria V. Yelshanskaya, Kei Saotome, Appu K. Singh, Alexander I. Sobolevsky
«Probing intersubunit interfaces in AMPA-subtype ionotropic glutamate receptors »,
Scientific Reports ,
2016, 6: 19082
Maria V. Yelshanskaya, Kei Saotome, Minfen Li, Alexander I. Sobolevsky
«Expression, purification, and crystallization of full length ionotropic glutamate receptors »,
Neuromethods ,
2016, IGRT: 83-100
2013 — earlier
Alexander I. Sobolevsky, Michael P. Rosconi, Eric Gouaux
«X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor »,
Nature ,
2009, 462 (7274): 745-56
Rongsheng Jin, Satinder K. Singh, Shenyan Gu, Hiroyasu Furukawa, Alexander I. Sobolevsky, Jie Zhou, Yan Jin, Eric Gouaux
«Crystal structure and association behaviour of the GluR2 amino-terminal domain »,
The EMBO Journal ,
2009, 28: 1812-1823
Alexander I. Sobolevsky, Michael L. Prodromou, Maria V. Yelshansky, Lonnie P. Wollmuth
«Subunit-specific contribution of pore-forming domains to NMDA receptor channel structure and gating »,
Journal of General Physiology ,
2007, 129 (6): 509-525
Maria V. Yelshansky, Alexander I. Sobolevsky, Claudia Jatzke, Lonnie P. Wollmuth
«Block of AMPA receptor desensitization by a point mutation outside the ligand-binding domain »,
Journal of Neuroscience ,
2004, 24 (20): 4728-4736
Alexander I. Sobolevsky, Maria V. Yelshansky, Lonnie P. Wollmuth
«The outer pore of the glutamate receptor channel has two-fold rotational symmetry »,
Neuron ,
2004, 41 (3): 367-378
Alexander I. Sobolevsky, Maria V. Yelshansky, Lonnie P. Wollmuth
«Different gating mechanisms in glutamate receptor and K+ channels »,
Journal of Neuroscience ,
2003, 23 (20): 7559-7568
Alexander I. Sobolevsky, LeeAnn Rooney, Lonnie P. Wollmuth
«Staggering of subunits in NMDAR channels »,
Biophysical Journal ,
2002, 83 (6): 3304-3314
Alexander I. Sobolevsky, Beck C., Lonnie P. Wollmuth
«Molecular rearrangements of the extracellular vestibule in NMDAR channels during gating »,
Neuron ,
2002, 33 (1): 75-85
02.08.2021
11.27.2020
10.29.2020
05.29.2020
04.03.2020