Publications
2019
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Appu K. Singh, Luke L. McGoldrick, Lusine Demirkhanyan, Merfilius Leslie, Eleonora Zakharian and Alexander I. Sobolevsky
«Structural basis of temperature sensation by the TRP channel TRPV3»,
Nature Structural & Molecular Biology,
2019, 26: 994–998
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Edward C. Twomey, Maria V. Yelshanskaya, Alexander I. Sobolevsky
«Structural and functional insights into transmembrane AMPA receptor regulatory protein complexes»,
Journal of General Physiology,
2019, 1540-7748
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Luke L. McGoldrick, Appu K. Singh, Lusine Demirkhanyan, Ting-Yu Lin, Ryan G. Casner, Eleonora Zakharian, Alexander I. Sobolevsky
«Structure of the Thermo-Sensitive TRP Channel TRP1 from the Alga Chlamydomonas Reinhardtii»,
Nature Communications,
2019, Sept 13; 10(1):4180.
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Lucie Macikova, Lenka Vyklicka, Ivan Barvik, Alexander I. Sobolevsky, Viktorie Vlachova
«Cytoplasmic Inter-Subunit Interface Controls Use-Dependence of Thermal Activation of TRPV3 Channel»,
International Journal of Molecular Science,
2019, 20(16), 3990
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Appu K. Singh, Luke L. McGoldrick, Alexander I. Sobolevsky
«Expression, Purification, and Crystallization of the Transient Receptor Potential Channel TRPV6»,
Methods in Molecular Biology ,
2019, volume 1987: pp 23-37
2018
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Alexander I. Sobolevsky
«Influences: Russian training»,
Journal of General Physiology,
2018, 150: 1596-1598
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Appu K. Singh*, Luke L. McGoldrick*, Alexander I. Sobolevsky
«Structure and gating mechanism of the transient receptor potential channel TRPV3»,
Nature Structural & Molecular Biology,
2018, 25: 805-813
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Edward C. Twomey, Maria V. Yelshanskaya, Alexander A. Vassilevski, Alexander I. Sobolevsky
«Mechanisms of channel block in calcium-permeable AMPA receptors»,
Neuron,
2018, 99: 956-968
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Appu K.Singh*, Luke McGodrick*, Edward C. Twomey, Alexander I. Sobolevsky
«Mechanism of calmodulin inactivation of the calcium-selective TRP channel TRPV6»,
Science Advances,
2018, 4 (8): eaau6088
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Appu K. Singh*, Kei Saotome*, Luke L. McGoldrick, Alexander I. Sobolevsky
«Structural bases of TRP channel TRPV6 allosteric modulation by 2-APB»,
Nature Communications,
2018, 9: 2465
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Appu K. Singh, Luke L. McGoldrick, Kei Saotome, Alexander I. Sobolevsky
«X-ray crystallography of TRP channels»,
Channels,
2018, 12: 137-152
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Serzhan Sakipov, Alexander I. Sobolevsky, Maria G. Kurnikova
«Ion permeation mechanism in epithelial calcium channel TRVP6»,
Scientific Reports,
2018, 8: 5715
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Dmitry I. Osmakov, Sergey G. Koshelev, Yaroslav A. Andreev, Maxim A. Dubinnyi, Vadim S. Kublitski, Roman G. Efremov, Alexander I. Sobolevsky, Sergey A. Kozlov
«Proton-independent activation of acid-sensing ion channel 3 by an alkaloid, lindoldhamine, from Laurus nobilis»,
British Journal of Pharmacology,
2018, 175 (6): 924-937
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Luke L. McGoldrick*, Appu K. Singh*, Kei Saotome, Maria V. Yelshanskaya, Edward C. Twomey, Robert A. Grassucci, Alexander I. Sobolevsky
«Opening of the human epithelial calcium channel TRPV6»,
Nature,
2018, 553: 233-237
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Edward C. Twomey, Alexander I. Sobolevsky
«Structural mechanisms of gating in ionotropic glutamate receptors»,
Biochemistry,
2018, 57 (3): 267-276
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Appu K. Singh, Kei Saotome, Alexander I. Sobolevsky
«Determining the crystal structure of TRPV6»,
Calcium Entry Channels in Non-Excitable Cells,
2018, ISBN 978-1-4987-5272-5
2017
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Appu K. Singh, Kei Saotome, Alexander I. Sobolevsky
«Swapping of transmembrane domains in the epithelial calcium channel TRPV6»,
Scientific Reports,
2017, 7: 10669
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Edward C. Twomey, Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, Alexander I. Sobolevsky
«Channel opening and gating mechanism in AMPA-subtype glutamate receptors»,
Nature,
2017, 549: 60-65
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Edward C. Twomey, Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, Alexander I. Sobolevsky
«Structural bases of desensitization in AMPA receptor-auxiliary subunit complexes»,
Neuron,
2017, 94 (3): 569-580.E5
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Maria V. Yelshanskaya, Samaneh Mesbahi-Vasey, Maria G. Kurnikova, Alexander I. Sobolevsky
«Role of the ion channel extracellular collar in AMPA receptor gating»,
Scientific Reports,
2017, 7: 1050
2016
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Maria V. Yelshanskaya, Appu K. Singh, Jared M. Sampson, Chamali Narangoda, Maria Kurnikova, Alexander I. Sobolevsky
«Structural bases of noncompetitive inhibition of AMPA-subtype ionotropic glutamate receptors by antiepileptic drugs»,
Neuron,
2016, 91 (6): 1305-1315
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Edward C. Twomey, Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, Alexander I. Sobolevsky
«Elucidation of AMPA receptor-stargazin complexes by cryo-electron microscopy»,
Science,
2016, 353 (6294): 83-86
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Kei Saotome, Appu K. Singh, Maria V. Yelshanskaya, Alexander I. Sobolevsky
«Crystal structure of the epithelial calcium channel TRPV6»,
Nature,
2016, 534: 506-511
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Maria V. Yelshanskaya, Kei Saotome, Appu K. Singh, Alexander I. Sobolevsky
«Probing intersubunit interfaces in AMPA-subtype ionotropic glutamate receptors»,
Scientific Reports,
2016, 6: 19082
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Maria V. Yelshanskaya, Kei Saotome, Minfen Li, Alexander I. Sobolevsky
«Expression, purification, and crystallization of full length ionotropic glutamate receptors»,
Neuromethods,
2016, IGRT: 83-100
2013 — earlier
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Alexander I. Sobolevsky, Michael P. Rosconi, Eric Gouaux
«X-ray structure, symmetry and mechanism of an AMPA-subtype glutamate receptor»,
Nature,
2009, 462 (7274): 745-56
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Rongsheng Jin, Satinder K. Singh, Shenyan Gu, Hiroyasu Furukawa, Alexander I. Sobolevsky, Jie Zhou, Yan Jin, Eric Gouaux
«Crystal structure and association behaviour of the GluR2 amino-terminal domain»,
The EMBO Journal,
2009, 28: 1812-1823
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Alexander I. Sobolevsky, Michael L. Prodromou, Maria V. Yelshansky, Lonnie P. Wollmuth
«Subunit-specific contribution of pore-forming domains to NMDA receptor channel structure and gating»,
Journal of General Physiology,
2007, 129 (6): 509-525
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Maria V. Yelshansky, Alexander I. Sobolevsky, Claudia Jatzke, Lonnie P. Wollmuth
«Block of AMPA receptor desensitization by a point mutation outside the ligand-binding domain»,
Journal of Neuroscience,
2004, 24 (20): 4728-4736
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Alexander I. Sobolevsky, Maria V. Yelshansky, Lonnie P. Wollmuth
«The outer pore of the glutamate receptor channel has two-fold rotational symmetry»,
Neuron,
2004, 41 (3): 367-378
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Alexander I. Sobolevsky, Maria V. Yelshansky, Lonnie P. Wollmuth
«Different gating mechanisms in glutamate receptor and K+ channels»,
Journal of Neuroscience,
2003, 23 (20): 7559-7568
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Alexander I. Sobolevsky, LeeAnn Rooney, Lonnie P. Wollmuth
«Staggering of subunits in NMDAR channels»,
Biophysical Journal,
2002, 83 (6): 3304-3314
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Alexander I. Sobolevsky, Beck C., Lonnie P. Wollmuth
«Molecular rearrangements of the extracellular vestibule in NMDAR channels during gating»,
Neuron,
2002, 33 (1): 75-85
